The Acid Test of Fluoride: How pH Modulates Toxicity
نویسندگان
چکیده
منابع مشابه
The Acid Test of Fluoride: How pH Modulates Toxicity
BACKGROUND It is not known why the ameloblasts responsible for dental enamel formation are uniquely sensitive to fluoride (F(-)). Herein, we present a novel theory with supporting data to show that the low pH environment of maturating stage ameloblasts enhances their sensitivity to a given dose of F(-). Enamel formation is initiated in a neutral pH environment (secretory stage); however, the pH...
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Molecular mechanisms of fluoride toxicity.
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0010895